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Grupo de Estudos em Amiloidose

Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo.

AL Amyloidosis ATTRv ATTRwt AA Amyloidosis 3 Rare Subtypes

Contact Information

Primary Contact

BRUNO VAZ KERGES BUENO

Coordinator of the Amyloidosis Fellowship

Activity level

  • Patients per year250
  • New diagnoses per year50

Multidisciplinary team

  • HematologyOn-site
  • CardiologyOn-site
  • NephrologyOn-site
  • NeurologyOn-site
  • PathologyOn-site
Other specialists
HepatologyPulmonologyRheumatologyGeneticistsGenetic counsellorsNuclear medicine specialistsCardiac imaging specialistsRadiologistsTransplant programme - heartTransplant programme - kidneyTransplant programme - liverAllied health professionals (NP, PA)Palliative care

Diagnostic capabilities

  • EchocardiographyOn-site
  • Cardiac MRI (CMR)On-site
  • Radionuclide imagingOn-site
  • Histopathology (Congo red)On-site
  • Amyloid typingOn-site
  • Genetic testingOn-site
  • Fat aspiration / labial gland biopsyOn-site
  • Organ biopsiesOn-site
Partner laboratories

Mass spectrometry is performed only in a partner laboratory.

Subtype expertise

  • ALYes
  • ATTRvYes
  • ATTRwtYes
  • AAYes
Rare subtypes
Apolipoprotein A-I (AApoA1)Apolipoprotein A-IV (AApoAIV)Fibrinogen A alpha-chain (AFib)
Referral pathways

Patients with fibrinogen and Apo were referred to the nephrology team for investigation of proteinuria and renal failure, as it is a quaternary reference service.

Treatment options

  • Chemotherapy (AL)Available via formal referral
  • TTR stabilizersAvailable on-site
  • RNA interferenceNot available
  • Antisense oligonucleotidesNot available
  • Stem cell transplantNot available
  • Heart transplantAvailable on-site
  • Kidney transplantAvailable on-site
  • Liver transplantAvailable on-site

Patient support services

Services offered
Social workGenetic counsellingSpecialty pharmacy

Networks & telemedicine

  • Telemedicine / virtual consultationYes
  • Part of a formal amyloidosis networkYes
  • Diagnostic services for other organisationsNo

Last confirmed: 28 March 2026

Listings are self-reported by each center and have not been independently verified by the International Society of Amyloidosis (ISA). Inclusion in this directory does not constitute certification, accreditation, or endorsement by ISA.