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National Heart Centre Singapore

Singhealth/National Heart Centre Singapore

AL Amyloidosis ATTRv ATTRwt

Contact Information

Primary Contact

Khoo Chun Yuan

Senior Consultant Cardiologist

Activity level

  • Patients per year100
  • New diagnoses per year15

Multidisciplinary team

  • HematologyThrough formal referral
  • CardiologyOn-site
  • NephrologyThrough formal referral
  • NeurologyThrough formal referral
  • PathologyOn-site
Other specialists
GastroenterologyHepatologyPulmonologyPrimary CareRheumatologyOrthopaedicsGeneticistsGenetic counsellorsNuclear medicine specialistsCardiac imaging specialistsRadiologistsTransplant programme - heartTransplant programme - kidneyTransplant programme - liverAllied health professionals (NP, PA)Palliative carePsychology / counsellingSocial work

Diagnostic capabilities

  • EchocardiographyOn-site
  • Cardiac MRI (CMR)On-site
  • Radionuclide imagingOn-site
  • Histopathology (Congo red)On-site
  • Amyloid typingThrough network partners
  • Genetic testingOn-site
  • Fat aspiration / labial gland biopsyOn-site
  • Organ biopsiesOn-site
Partner laboratories

We send our congo-red positive biopsies to Mayo Clinic Laboratories for mass spectrometry

Subtype expertise

  • ALYes
  • ATTRvYes
  • ATTRwtYes
  • AANo

Treatment options

  • Chemotherapy (AL)Available via formal referral
  • TTR stabilizersAvailable on-site
  • RNA interferenceAvailable on-site
  • Antisense oligonucleotidesAvailable on-site
  • Stem cell transplantAvailable via formal referral
  • Heart transplantAvailable on-site
  • Kidney transplantAvailable via formal referral
  • Liver transplantAvailable via formal referral
Other therapeutic services

Due to the limitation of donor solid organ availability in Singapore, patients with ATTR and AL do not typically get evaluated for heart/kidney transplant.
Liver transplant has been phased out following the availability of amyloid specific therapies.
We are under the same umbrella institution (Singhealth, Singapore General Hospital) where our hematologist provides treatment (chemotherapy/stemcell transplants) for AL amyloid patients in the same hospital campus.

Patient support services

Services offered
Psychosocial supportSocial workGenetic counsellingNutritional guidance (dietitian)Specialty pharmacyPalliative careFinancial or access counselling

Networks & telemedicine

  • Telemedicine / virtual consultationYes
  • Part of a formal amyloidosis networkNo
  • Diagnostic services for other organisationsNo

Last confirmed: 30 March 2026

Listings are self-reported by each center and have not been independently verified by the International Society of Amyloidosis (ISA). Inclusion in this directory does not constitute certification, accreditation, or endorsement by ISA.